BEGIN:VCALENDAR PRODID:-//Microsoft Corporation//Outlook MIMEDIR//EN VERSION:1.0 BEGIN:VEVENT DTSTART:20111116T011500Z DTEND:20111116T030000Z LOCATION:WSCC North Galleria 2nd/3rd Floors DESCRIPTION;ENCODING=QUOTED-PRINTABLE:ABSTRACT: Data intensive computing has the potential to change biosurveillance. Biosurveillance requires the ability to ‘connect the dots’ and inform decision makers in near real-time. To do this effectively, computers need to handle information found on the web as diverse as DNA sequence and social media posts. A key challenge to process the web in near real-time is the rapid conversion of petabytes of raw information into a semantically rich and query-able knowledgebase that serves decision support needs. We present a novel architecture that combines: (1) parallel web crawlers guided by biological ontologies to extract relevant information, (2) a petascale cache to store, classify, index and cluster those portions of the web relevant to biosurveillance, and (3) a semantic store to integrate diverse sources of data, guide new searches and serve as a platform for data analysis and user applications. A poster and handouts will be available at the conference. SUMMARY:A Novel Architecture for Biothreat Situation Awareness PRIORITY:3 END:VEVENT END:VCALENDAR